NAA15 gene

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes the auxillary subunit of the N-terminal acetyltransferase A (NatA) complex. [provided by RefSeq, Jan 2017]

From UniProt:

Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.

From NCBI Gene:

  • MENTAL RETARDATION, AUTOSOMAL DOMINANT 50

From UniProt:

Mental retardation, autosomal dominant 50 (MRD50): A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. [MIM:617787]

Cytogenetic Location: 4q31.1, which is the long (q) arm of chromosome 4 at position 31.1

Molecular Location: base pairs 139,301,467 to 139,390,781 on chromosome 4 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 4q31.1, which is the long (q) arm of chromosome 4 at position 31.1
  • Ga19
  • MRD50
  • NARG1
  • NAT1P
  • NATH
  • TBDN
  • TBDN100