MTNR1B gene

melatonin receptor 1B

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]

From UniProt:

High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Cytogenetic Location: 11q14.3, which is the long (q) arm of chromosome 11 at position 14.3

Molecular Location: base pairs 92,969,623 to 92,986,241 on chromosome 11 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 11q14.3, which is the long (q) arm of chromosome 11 at position 14.3
  • FGQTL2
  • MEL-1B-R
  • MT2