MSMB gene

microseminoprotein beta

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Covered on Genetics Home Reference:

From NCBI Gene:

  • Prostate cancer, hereditary, 13

From UniProt:

Prostate cancer, hereditary, 13 (HPC13): A condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. [MIM:611928]

Cytogenetic Location: 10q11.22, which is the long (q) arm of chromosome 10 at position 11.22

Molecular Location: base pairs 46,033,305 to 46,046,269 on chromosome 10 (Homo sapiens Updated Annotation Release 109.20200522, GRCh38.p13) (NCBI)

Cytogenetic Location: 10q11.22, which is the long (q) arm of chromosome 10 at position 11.22
  • HPC13
  • IGBF
  • MSP
  • MSPB
  • PN44
  • PRPS
  • PSP
  • PSP-94
  • PSP57
  • PSP94