MRAS gene

muscle RAS oncogene homolog

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

From UniProt:

May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.

Cytogenetic Location: 3q22.3, which is the long (q) arm of chromosome 3 at position 22.3

Molecular Location: base pairs 138,347,648 to 138,405,535 on chromosome 3 (Homo sapiens Updated Annotation Release 109.20190905, GRCh38.p13) (NCBI)

Cytogenetic Location: 3q22.3, which is the long (q) arm of chromosome 3 at position 22.3
  • M-RAs
  • NS11
  • R-RAS3
  • RRAS3