MFF gene

From NCBI Gene:

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

From UniProt:

Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.

From NCBI Gene:

• ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2

Cytogenetic Location: 2q36.3, which is the long (q) arm of chromosome 2 at position 36.3

Molecular Location: base pairs 227,325,151 to 227,357,836 on chromosome 2 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

• C2orf33
• EMPF2
• GL004