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Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes.
Covered on Genetics Home Reference:
Susceptibility to azoospermia may be associated with MEI1 variations.
Cytogenetic Location: 22q13.2, which is the long (q) arm of chromosome 22 at position 13.2
Molecular Location: base pairs 41,699,503 to 41,799,477 on chromosome 22 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)
Published: March 19, 2019
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