MEI1 gene

meiotic double-stranded break formation protein 1

The information on this page was automatically extracted from online scientific databases.

From UniProt:

Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity).

Covered on Genetics Home Reference:

From NCBI Gene:

  • HYDATIDIFORM MOLE, RECURRENT, 3

From UniProt:

Hydatidiform mole, recurrent, 3 (HYDM3): A disorder characterized by excessive trophoblast development that produces a growing mass of tissue inside the uterus at the beginning of a pregnancy. It leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi. [MIM:618431]

Susceptibility to azoospermia may be associated with MEI1 variations.

Cytogenetic Location: 22q13.2, which is the long (q) arm of chromosome 22 at position 13.2

Molecular Location: base pairs 41,699,503 to 41,799,477 on chromosome 22 (Homo sapiens Updated Annotation Release 109.20200228, GRCh38.p13) (NCBI)

Cytogenetic Location: 22q13.2, which is the long (q) arm of chromosome 22 at position 13.2
  • HYDM3
  • SPATA38