MED12L gene

mediator complex subunit 12L

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]

From UniProt:

May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Cytogenetic Location: 3q25.1, which is the long (q) arm of chromosome 3 at position 25.1

Molecular Location: base pairs 151,085,665 to 151,436,677 on chromosome 3 (Homo sapiens Updated Annotation Release 109.20200522, GRCh38.p13) (NCBI)

Cytogenetic Location: 3q25.1, which is the long (q) arm of chromosome 3 at position 25.1
  • NIZIDS
  • NOPAR
  • TNRC11L
  • TRALP
  • TRALPUSH