LHFP gene

lipoma HMGIC fusion partner

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. [provided by RefSeq, Jul 2008]

From UniProt:

A chromosomal aberration involving LHFP is associated with a subclass of benign mesenchymal tumors known as lipomas. Translocation t(12;13)(q13-q15;q12) with HMGA2 is shown in lipomas.

Cytogenetic Location: 13q12, which is the long (q) arm of chromosome 13 at position 12

Molecular Location: base pairs 39,342,892 to 39,603,219 on chromosome 13 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 13q12, which is the long (q) arm of chromosome 13 at position 12