LDHD gene

lactate dehydrogenase D

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

From UniProt:

Involved in D-lactate, but not L-lactate catabolic process.

From NCBI Gene:

  • Lactic aciduria due to d-lactic acid

From UniProt:

D-lactic aciduria (DLACD): An autosomal recessive metabolic disorder characterized by D-lactic aciduria in the presence of normal plasma lactic acid. [MIM:245450]

Cytogenetic Location: 16q23.1, which is the long (q) arm of chromosome 16 at position 23.1

Molecular Location: base pairs 75,111,860 to 75,116,795 on chromosome 16 (Homo sapiens Updated Annotation Release 109.20190905, GRCh38.p13) (NCBI)

Cytogenetic Location: 16q23.1, which is the long (q) arm of chromosome 16 at position 23.1
  • DLACD
  • DLD