KIZ gene

kizuna centrosomal protein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

From UniProt:

Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.

From NCBI Gene:

  • Retinitis pigmentosa 69

From UniProt:

Retinitis pigmentosa 69 (RP69): A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. [MIM:615780]

Cytogenetic Location: 20p11.23, which is the short (p) arm of chromosome 20 at position 11.23

Molecular Location: base pairs 21,125,980 to 21,246,628 on chromosome 20 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 20p11.23, which is the short (p) arm of chromosome 20 at position 11.23
  • C20orf19
  • HT013
  • Kizuna
  • NCRNA00153
  • PLK1S1
  • RP69