KEL gene

Kell blood group, metallo-endopeptidase

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]

From UniProt:

Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.

Cytogenetic Location: 7q34, which is the long (q) arm of chromosome 7 at position 34

Molecular Location: base pairs 142,941,114 to 142,962,416 on chromosome 7 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 7q34, which is the long (q) arm of chromosome 7 at position 34
  • CD238
  • ECE3