KDM5D gene

lysine demethylase 5D

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

From UniProt:

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.

Cytogenetic Location: Yq11, which is the long (q) arm of the Y chromosome at position 11

Molecular Location: base pairs 19,692,495 to 19,745,347 on the Y chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Yq11, which is the long (q) arm of the Y chromosome at position 11
  • HY
  • HYA
  • JARID1D
  • SMCY