ITPR3 gene

inositol 1,4,5-trisphosphate receptor type 3

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]

From UniProt:

Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Diabetes mellitus type 1

Cytogenetic Location: 6p21.31, which is the short (p) arm of chromosome 6 at position 21.31

Molecular Location: base pairs 33,621,333 to 33,696,574 on chromosome 6 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 6p21.31, which is the short (p) arm of chromosome 6 at position 21.31
  • IP3R
  • IP3R3