IRF2BP2 gene

interferon regulatory factor 2 binding protein 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

From UniProt:

Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle.

Cytogenetic Location: 1q42.3, which is the long (q) arm of chromosome 1 at position 42.3

Molecular Location: base pairs 234,604,269 to 234,609,525 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q42.3, which is the long (q) arm of chromosome 1 at position 42.3
  • CVID14