IMMP2L gene

inner mitochondrial membrane peptidase subunit 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]

From UniProt:

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

From UniProt:

Gilles de la Tourette syndrome (GTS): Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. [MIM:137580]

Cytogenetic Location: 7q31, which is the long (q) arm of chromosome 7 at position 31

Molecular Location: base pairs 110,662,645 to 111,562,531 on chromosome 7 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 7q31, which is the long (q) arm of chromosome 7 at position 31
  • IMMP2L-IT1
  • IMP2
  • IMP2-LIKE