IFT81 gene

intraflagellar transport 81

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene, together with IFT74, forms a tubulin-binding module of intraflagellar transport complex B. This module is involved in transport of tubulin within the cilium, and the encoded protein is required for ciliogenesis. Mutations in this gene are a cause of short-rib polydactyly syndromes. [provided by RefSeq, Dec 2016]

From UniProt:

Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis.

From NCBI Gene:

  • SHORT-RIB THORACIC DYSPLASIA 19 WITH OR WITHOUT POLYDACTYLY

Cytogenetic Location: 12q24.11, which is the long (q) arm of chromosome 12 at position 24.11

Molecular Location: base pairs 110,124,335 to 110,218,795 on chromosome 12 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 12q24.11, which is the long (q) arm of chromosome 12 at position 24.11
  • CDV-1
  • CDV-1R
  • CDV1
  • CDV1R
  • DV1
  • SRTD19