HOXB1 gene

homeobox B1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008]

From UniProt:

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.

From NCBI Gene:

  • Hereditary congenital facial paresis 3

From UniProt:

Facial paresis, hereditary congenital, 3 (HCFP3): A form of facial paresis, a disease characterized by isolated dysfunction of the facial nerve (CN VII). HCFP3 patients are affected by bilateral facial palsy, facial muscle weakness of muscles innervated by CN VII, hearing loss, and strabismus. [MIM:614744]

Cytogenetic Location: 17q21.32, which is the long (q) arm of chromosome 17 at position 21.32

Molecular Location: base pairs 48,529,445 to 48,530,910 on chromosome 17 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 17q21.32, which is the long (q) arm of chromosome 17 at position 21.32
  • HCFP3
  • Hox-2.9
  • HOX2
  • HOX2I