H6PD gene

hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells. [provided by RefSeq, Jul 2008]

From UniProt:

Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.

From NCBI Gene:

  • Cortisone reductase deficiency 1

From UniProt:

Cortisone reductase deficiency (CRD): In CRD, activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotype resembling polycystic ovary syndrome (PCOS). [MIM:604931]

Cytogenetic Location: 1p36.22, which is the short (p) arm of chromosome 1 at position 36.22

Molecular Location: base pairs 9,234,767 to 9,271,337 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p36.22, which is the short (p) arm of chromosome 1 at position 36.22
  • CORTRD1
  • G6PDH
  • GDH