GRXCR2 gene

glutaredoxin and cysteine rich domain containing 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein containing a glutaredoxin domain, which functions in protein S-glutathionylation. A mutation in this gene was found in a family with autoosomal recessive nonsyndromic sensorineural deafness-101. [provided by RefSeq, Jun 2014]

From UniProt:

Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Deafness, autosomal recessive 101

From UniProt:

Deafness, autosomal recessive, 101 (DFNB101): A form of non-syndromic deafness characterized by bilateral, moderate to severe hearing loss. Vestibular function is unaffected. [MIM:615837]

Cytogenetic Location: 5q32, which is the long (q) arm of chromosome 5 at position 32

Molecular Location: base pairs 145,858,538 to 145,931,673 on chromosome 5 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 5q32, which is the long (q) arm of chromosome 5 at position 32
  • DFNB101