GREB1L gene

GREB1 like retinoic acid receptor coactivator

The information on this page was automatically extracted from online scientific databases.

From UniProt:

Plays a major role in early metanephros and genital development.

Covered on Genetics Home Reference:

From NCBI Gene:

  • RENAL HYPODYSPLASIA/APLASIA 3

From UniProt:

Renal hypodysplasia/aplasia 3 (RHDA3): A severe, autosomal dominant disease encompassing a spectrum of kidney development defects. Clinical manifestations are highly variable and include bilateral or unilateral renal agenesis, renal aplasia, hypoplasia, (cystic) dysplasia, severe obstructive uropathy, and vesicoureteral reflux. Bilateral renal agenesis is almost invariably fatal in utero or in the perinatal period. Unilateral renal agenesis can lead to future health issues including end-stage renal disease. [MIM:617805]

Cytogenetic Location: 18q11.1-q11.2, which is the long (q) arm of chromosome 18 between positions 11.1 and 11.2

Molecular Location: base pairs 21,242,225 to 21,528,503 on chromosome 18 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 18q11.1-q11.2, which is the long (q) arm of chromosome 18 between positions 11.1 and 11.2
  • C18orf6
  • KIAA1772
  • RHDA3