GPC4 gene

glypican 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]

From UniProt:

Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.

From NCBI Gene:

  • Wilms tumor 1
  • Simpson-Golabi-Behmel syndrome

Cytogenetic Location: Xq26.1, which is the long (q) arm of the X chromosome at position 26.1

Molecular Location: base pairs 133,301,036 to 133,415,177 on the X chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Xq26.1, which is the long (q) arm of the X chromosome at position 26.1
  • K-glypican