GIPC3 gene

GIPC PDZ domain containing family member 3

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2011]

From UniProt:

Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Deafness, autosomal recessive 15

From UniProt:

Deafness, autosomal recessive, 15 (DFNB15): A form of non-syndromic sensorineural hearing loss with prelingual onset. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. [MIM:601869]

Cytogenetic Location: 19p13.3, which is the short (p) arm of chromosome 19 at position 13.3

Molecular Location: base pairs 3,585,531 to 3,593,541 on chromosome 19 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 19p13.3, which is the short (p) arm of chromosome 19 at position 13.3
  • C19orf64
  • DFNB15
  • DFNB72
  • DFNB95