COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.
Get the latest research from NIH: https://www.nih.gov/coronavirus.

As of October 1, 2020, the National Library of Medicine (NLM) will no longer offer Genetics Home Reference as a stand-alone website. Instead, much of the content from Genetics Home Reference has been transferred to MedlinePlus, the NLM’s flagship website for health information for patients, families, and the general public.

Please visit MedlinePlus Genetics (https://medlineplus.gov/genetics) to access genetics information and learn more about this change.

GAS7 gene

growth arrest specific 7

Open All Close All

The information on this page was automatically extracted from online scientific databases.

Normal Function

From NCBI Gene:

Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008]

May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

Health Conditions Related to Genetic Changes

A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with KMT2A/MLL1.

Chromosomal Location

Cytogenetic Location: 17p13.1, which is the short (p) arm of chromosome 17 at position 13.1

Molecular Location: base pairs 9,910,606 to 10,198,606 on chromosome 17 (Homo sapiens Updated Annotation Release 109.20200522, GRCh38.p13) (NCBI)

Cytogenetic Location: 17p13.1, which is the short (p) arm of chromosome 17 at position 13.1

Credit: Genome Decoration Page/NCBI

Additional Information & Resources

Tests Listed in the Genetic Testing Registry (1 link)

Tests of GAS7

Catalog of Genes and Diseases from OMIM (1 link)

OMIM: GROWTH ARREST-SPECIFIC 7

Research Resources (5 links)

Published: August 17, 2020

The resources on this site should not be used as a substitute for professional medical care or advice. Users with questions about a personal health condition should consult with a qualified healthcare professional.