GABRA5 gene

gamma-aminobutyric acid type A receptor alpha5 subunit

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]

From UniProt:

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Cytogenetic Location: 15q12, which is the long (q) arm of chromosome 15 at position 12

Molecular Location: base pairs 26,866,719 to 26,949,210 on chromosome 15 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 15q12, which is the long (q) arm of chromosome 15 at position 12