FYB gene

FYN binding protein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

From UniProt:

Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.

Cytogenetic Location: 5p13.1, which is the short (p) arm of chromosome 5 at position 13.1

Molecular Location: base pairs 39,105,252 to 39,274,523 on chromosome 5 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 5p13.1, which is the short (p) arm of chromosome 5 at position 13.1
  • ADAP
  • PRO0823
  • SLAP-130
  • SLAP130
  • THC3