FUT2 gene

fucosyltransferase 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

From UniProt:

Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.

From NCBI Gene:

  • Vitamin b12 plasma level quantitative trait locus 1

Cytogenetic Location: 19q13.3, which is the long (q) arm of chromosome 19 at position 13.3

Molecular Location: base pairs 48,695,971 to 48,705,934 on chromosome 19 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 19q13.3, which is the long (q) arm of chromosome 19 at position 13.3
  • B12QTL1
  • SE
  • Se2
  • SEC2
  • sej