FRMPD4 gene

FERM and PDZ domain containing 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. [provided by RefSeq, Jan 2010]

From UniProt:

Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.

From NCBI Gene:

  • Autism, susceptibility to, X-linked 4
  • MENTAL RETARDATION, X-LINKED 104

Cytogenetic Location: Xp22.2, which is the short (p) arm of the X chromosome at position 22.2

Molecular Location: base pairs 12,137,329 to 12,724,523 on the X chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Xp22.2, which is the short (p) arm of the X chromosome at position 22.2
  • MRX104
  • PDZD10
  • PDZK10