FRK gene

fyn related Src family tyrosine kinase

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]

From UniProt:

Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.

Cytogenetic Location: 6q22.1, which is the long (q) arm of chromosome 6 at position 22.1

Molecular Location: base pairs 115,941,031 to 116,100,739 on chromosome 6 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 6q22.1, which is the long (q) arm of chromosome 6 at position 22.1
  • GTK
  • PTK5
  • RAK