FOXH1 gene
forkhead box H1
The information on this page was automatically extracted from online scientific databases.
From NCBI Gene:
FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT. [provided by RefSeq, Jul 2008]
From UniProt:
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Related Information
Covered on Genetics Home Reference:
Related Information
Cytogenetic Location: 8q24.3, which is the long (q) arm of chromosome 8 at position 24.3
Molecular Location: base pairs 144,473,732 to 144,476,335 on chromosome 8 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Related Information
- FAST-1
- FAST1