FOXH1 gene

From NCBI Gene:

FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT. [provided by RefSeq, Jul 2008]

From UniProt:

Covered on Genetics Home Reference:

• Heterotaxy syndrome
• Nonsyndromic holoprosencephaly
• Critical congenital heart disease

Cytogenetic Location: 8q24.3, which is the long (q) arm of chromosome 8 at position 24.3

Molecular Location: base pairs 144,473,732 to 144,476,335 on chromosome 8 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

• FAST-1
• FAST1