FCRL5 gene

Fc receptor like 5

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

From UniProt:

May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.

From UniProt:

A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32).

Cytogenetic Location: 1q21, which is the long (q) arm of chromosome 1 at position 21

Molecular Location: base pairs 157,513,377 to 157,552,520 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q21, which is the long (q) arm of chromosome 1 at position 21
  • BXMAS1
  • CD307
  • CD307e
  • FCRH5
  • IRTA2
  • PRO820