FCGR2A gene

Fc fragment of IgG receptor IIa

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

From UniProt:

Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Systemic lupus erythematosus
  • Susceptibility to malaria

Cytogenetic Location: 1q23.3, which is the long (q) arm of chromosome 1 at position 23.3

Molecular Location: base pairs 161,505,415 to 161,524,048 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q23.3, which is the long (q) arm of chromosome 1 at position 23.3
  • CD32
  • CD32A
  • CDw32
  • FCG2
  • FcGR
  • FCGR2
  • FCGR2A1
  • IGFR2