FARSB gene

phenylalanyl-tRNA synthetase subunit beta

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

From NCBI Gene:

  • NEURODEVELOPMENTAL DISORDER WITH BRAIN, LIVER, AND LUNG ABNORMALITIES

Cytogenetic Location: 2q36.1, which is the long (q) arm of chromosome 2 at position 36.1

Molecular Location: base pairs 222,571,443 to 222,656,355 on chromosome 2 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 2q36.1, which is the long (q) arm of chromosome 2 at position 36.1
  • FARSLB
  • FRSB
  • HSPC173
  • NEDBLLA
  • PheHB
  • PheRS