EN2 gene

engrailed homeobox 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]

From UniProt:

Genetic variations in EN2 may be associated with susceptibility to autism.

Cytogenetic Location: 7q36, which is the long (q) arm of chromosome 7 at position 36

Molecular Location: base pairs 155,458,129 to 155,464,831 on chromosome 7 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 7q36, which is the long (q) arm of chromosome 7 at position 36