ELP2 gene

elongator acetyltransferase complex subunit 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin. [provided by RefSeq, May 2016]

From UniProt:

Regulates the ligand-dependent activation of STAT3.

Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

From NCBI Gene:

  • MENTAL RETARDATION, AUTOSOMAL RECESSIVE 58

Cytogenetic Location: 18q12.2, which is the long (q) arm of chromosome 18 at position 12.2

Molecular Location: base pairs 36,129,874 to 36,177,931 on chromosome 18 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 18q12.2, which is the long (q) arm of chromosome 18 at position 12.2
  • MRT58
  • SHINC-2
  • STATIP1
  • StIP