EDC3 gene

enhancer of mRNA decapping 3

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]

From UniProt:

Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis.

From NCBI Gene:

  • Mental retardation, autosomal recessive 50

From UniProt:

Mental retardation, autosomal recessive 50 (MRT50): A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRT50 patients show mild intellectual disability and microcephaly. [MIM:616460]

Cytogenetic Location: 15q24.1, which is the long (q) arm of chromosome 15 at position 24.1

Molecular Location: base pairs 74,630,558 to 74,696,045 on chromosome 15 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 15q24.1, which is the long (q) arm of chromosome 15 at position 24.1
  • hYjeF_N2-15q23
  • LSM16
  • MRT50
  • YJDC
  • YJEFN2