DVL3 gene

dishevelled segment polarity protein 3

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]

From UniProt:

May play a role in the signal transduction pathway mediated by multiple Wnt genes.

From NCBI Gene:

  • Robinow syndrome, autosomal dominant 3

From UniProt:

Robinow syndrome, autosomal dominant 3 (DRS3): A form of Robinow syndrome, a rare skeletal dysplasia syndrome characterized by dysmorphic features resembling a fetal face, mesomelic limb shortening, genital hypoplasia, renal anomalies, and costovertebral segmentation defects. [MIM:616894]

Cytogenetic Location: 3q27, which is the long (q) arm of chromosome 3 at position 27

Molecular Location: base pairs 184,155,311 to 184,173,614 on chromosome 3 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 3q27, which is the long (q) arm of chromosome 3 at position 27