DSTYK gene

dual serine/threonine and tyrosine protein kinase

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

From UniProt:

Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death.

From NCBI Gene:

  • Congenital anomalies of kidney and urinary tract 1, susceptibility to

From UniProt:

Congenital anomalies of the kidney and urinary tract 1 (CAKUT1): A disorder encompassing a broad spectrum of renal and urinary tract malformations that include renal agenesis, kidney hypodysplasia, multicystic kidney dysplasia, duplex collecting system, posterior urethral valves and ureter abnormalities. Congenital anomalies of kidney and urinary tract are the commonest cause of chronic kidney disease in children. [MIM:610805]

Cytogenetic Location: 1q32.1, which is the long (q) arm of chromosome 1 at position 32.1

Molecular Location: base pairs 205,142,497 to 205,211,599 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q32.1, which is the long (q) arm of chromosome 1 at position 32.1
  • CAKUT1
  • DustyPK
  • HDCMD38P
  • RIP5
  • RIPK5