DRD2

dopamine receptor D2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

From UniProt:

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Myoclonic dystonia

Cytogenetic Location: 11q23, which is the long (q) arm of chromosome 11 at position 23

Molecular Location: base pairs 113,409,595 to 113,475,279 on chromosome 11 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 11q23, which is the long (q) arm of chromosome 11 at position 23
  • D2DR
  • D2R