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Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
Covered on Genetics Home Reference:
Cytogenetic Location: 13q32.3, which is the long (q) arm of chromosome 13 at position 32.3
Molecular Location: base pairs 98,793,429 to 99,086,694 on chromosome 13 (Homo sapiens Updated Annotation Release 109.20190607, GRCh38.p13) (NCBI)
Published: August 6, 2019
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