DIRC1 gene

disrupted in renal carcinoma 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation is associated with familial clear cell renal cancer. Overexpression of this gene is associated with tumor progression and poor prognosis in gastric cancer. [provided by RefSeq, Mar 2019]

From UniProt:

A chromosomal aberration involving DIRC1 is associated with familial clear cell renal carcinoma (PubMed:11587072). Translocation t(2;3)(q33;q21) (PubMed:11587072).

Cytogenetic Location: 2q32.2, which is the long (q) arm of chromosome 2 at position 32.2

Molecular Location: base pairs 188,733,738 to 188,790,104 on chromosome 2 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 2q32.2, which is the long (q) arm of chromosome 2 at position 32.2