DHX38 gene

DEAH-box helicase 38

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008]

From UniProt:

Probable ATP-binding RNA helicase involved in pre-mRNA splicing.

Cytogenetic Location: 16q22.2, which is the long (q) arm of chromosome 16 at position 22.2

Molecular Location: base pairs 72,093,665 to 72,112,912 on chromosome 16 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 16q22.2, which is the long (q) arm of chromosome 16 at position 22.2
  • DDX38
  • PRP16
  • PRPF16