DAOA gene

D-amino acid oxidase activator

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]

From UniProt:

Seems to activate D-amino acid oxidase.

Cytogenetic Location: 13q33.2, which is the long (q) arm of chromosome 13 at position 33.2

Molecular Location: base pairs 105,465,867 to 105,491,034 on chromosome 13 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 13q33.2, which is the long (q) arm of chromosome 13 at position 33.2
  • LG72
  • SG72