DAB1 gene

DAB1, reelin adaptor protein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]

From UniProt:

Adapter molecule functioning in neural development. May regulate SIAH1 activity.

Cytogenetic Location: 1p32.2, which is the short (p) arm of chromosome 1 at position 32.2

Molecular Location: base pairs 56,997,906 to 58,250,539 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p32.2, which is the short (p) arm of chromosome 1 at position 32.2