CSF2RB

colony stimulating factor 2 receptor beta common subunit

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]

From UniProt:

High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Surfactant metabolism dysfunction, pulmonary, 5

From UniProt:

Pulmonary surfactant metabolism dysfunction 5 (SMDP5): A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. [MIM:614370]

Cytogenetic Location: 22q13.1, which is the long (q) arm of chromosome 22 at position 13.1

Molecular Location: base pairs 36,913,574 to 36,940,449 on chromosome 22 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 22q13.1, which is the long (q) arm of chromosome 22 at position 13.1
  • CD131
  • CDw131
  • IL3RB
  • IL5RB
  • SMDP5