CRIM1 gene

cysteine rich transmembrane BMP regulator 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]

From UniProt:

May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.

Cytogenetic Location: 2p22.2, which is the short (p) arm of chromosome 2 at position 22.2

Molecular Location: base pairs 36,356,088 to 36,551,135 on chromosome 2 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 2p22.2, which is the short (p) arm of chromosome 2 at position 22.2
  • CRIM-1
  • S52