COG2 gene

component of oligomeric golgi complex 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]

From UniProt:

Required for normal Golgi morphology and function.

From NCBI Gene:

  • CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIq

Cytogenetic Location: 1q42.2, which is the long (q) arm of chromosome 1 at position 42.2

Molecular Location: base pairs 230,642,456 to 230,693,985 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q42.2, which is the long (q) arm of chromosome 1 at position 42.2
  • CDG2Q
  • LDLC