CNKSR2 gene

connector enhancer of kinase suppressor of Ras 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

From UniProt:

May function as an adapter protein or regulator of Ras signaling pathways.

From NCBI Gene:

  • MENTAL RETARDATION, X-LINKED, SYNDROMIC, HOUGE TYPE

Cytogenetic Location: Xp22.12, which is the short (p) arm of the X chromosome at position 22.12

Molecular Location: base pairs 21,374,298 to 21,654,695 on the X chromosome (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: Xp22.12, which is the short (p) arm of the X chromosome at position 22.12
  • CNK2
  • KSR2
  • MAGUIN
  • MRXSHG