CIZ1 gene

CDKN1A interacting zinc finger protein 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

From UniProt:

May regulate the subcellular localization of CIP/WAF1.

From UniProt:

Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk.

Cytogenetic Location: 9q34.1, which is the long (q) arm of chromosome 9 at position 34.1

Molecular Location: base pairs 128,166,065 to 128,204,383 on chromosome 9 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 9q34.1, which is the long (q) arm of chromosome 9 at position 34.1
  • LSFR1
  • NP94
  • ZNF356