CHIC2 gene

cysteine rich hydrophobic domain 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]

From UniProt:

A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.

Cytogenetic Location: 4q11, which is the long (q) arm of chromosome 4 at position 11

Molecular Location: base pairs 53,996,335 to 54,064,648 on chromosome 4 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 4q11, which is the long (q) arm of chromosome 4 at position 11