CFHR4 gene

complement factor H related 4

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011]

From UniProt:

Involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.

Cytogenetic Location: 1q31.3, which is the long (q) arm of chromosome 1 at position 31.3

Molecular Location: base pairs 196,888,014 to 196,918,911 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q31.3, which is the long (q) arm of chromosome 1 at position 31.3
  • CFHL4
  • FHR-4
  • FHR4